High Shear Mixers and Granulators
Aeromatic-Fielder™ High Shear bottom-drive Mixing and Granulation with PMA™ range
The GEA Pharma Systems - Aeromatic-Fielder™ High Shear Mixer and Granulator is a multi-purpose processor equally suitable for high speed dispersion of dry powders, aqueous or solvent granulations, effervescent products and melt pelletization ... Read more and download
Collette™ High Shear top-drive Mixing and Granulation with UltimaGral™ range
Whether the customer’s requirement is for mixing or granulation, GEA Pharma Systems / Collette™ has a solution for every processing challenge. With both low shear planetary mixers and high shear granulators in the range, Collette can help select the technology that is most suitable for the product and process ... Read more and download
PharmaConnect® Modules
PharmaConnect® ‘plug and play’ approach enables a number of diverse process modules from GEA Pharma Systems brands to be docked to ONE control module. The primary processes are based around Aeromatic-Fielder’s PMA™ Granulator technology, providing the user with the ability to process batches from 100g up to 25kg and over ...
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Technology up-date: Safety 1st - with new 16 bar High Shear Granulators from Aeromatic-Fielder™ and Collette™
Extensive safety testing confirms pressure enhancement effects and identifies safe design limits for integrated granulation and drying systems. GEA Pharma Systems (formerly known as Niro Pharma Systems) in conjunction with FSA, the safety specialist centre in Germany, have carried out an extensive test program involving over 100 test explosions. This research has shown conclusively that should an explosion occur during the transfer operation in an integrated granulation and drying system where a granulator is connected directly to a fluid bed dryer without an explosion isolation valve then, the secondary explosion pressures in the granulator can be significantly higher than in the fluid bed. These tests have enabled GEA Pharma Systems to gain full EC type approval for a range of pressure shock resistant integrated systems and 16 bar pressure shock resistant high shear granulators. The tests were carried out with hybrid mixtures which behave in the same way as pharmaceutical products containing organic solvents and showed that that the final explosion pressure in the granulator is dependent on the volumes of the two vessels and that the length and diameter of the interconnecting duct is critical in ensuring that the pressure remains within safe limits ... Read more
Deutsch: Die neue Granulierlinie der Solida-Produktion Roche Basel
Als Ersatz für ältere Prozessanlagen gaben die Fachleute der Solida-Produktion (Herstellung
fester Arzneiformen im Bereich Galenik) im Herbst 2003 eine neue Granulierlinie in Auftrag, die den heutigen Anforderungen entspricht. Der Hauptapparat, bestehend aus einem mehr als sechs Meter hohen Wirbelschichttrockner, wurde Ende Juli vergangenen Jahres mittels eines Lastwagenkrans ins zweite Geschoss des Pharmagebäudes 27 eingebracht. (Vergleiche Roche Nachrichten 2004/8, Seite 16.) In der Folge wurde die gesamte Anlage, die zwei Stockwerke beansprucht, durch die verschiedenen Lieferanten, Spezialisten und Monteure Schritt für Schritt installiert, überprüft und qualifiziert ... Read more and download