A process analysing, monitoring and control tool for Freeze Drying in R+D applications and for full-scale production.
Freeze Drying Cycle with Thermodynamic Lyophilization Control
GEA Lyophil has developed TLC as an in-line, non-invasive method of:
- Monitoring the primary (main) drying
- Determining the end of the main drying
- Monitoring the secondary drying
- Determining the end of the secondary
drying
TLC enables a dynamic control of the drying process: minor variations – e.g. of the raw product or the filling height of the vials – will be identified and the process will be adjusted accordingly.
Advantages:
- Applicable for all freeze dryers
- Ideal for sterile processing
- Ideal with automatic loading and unloading systems
- Ideal when isolator technology is used
- No need for mechanical modifications at the lyophilizer
- No risk of contamination
- Reproducible measurements
- Direct & accurate lyophilization monitoring and control
- Monitoring of the complete batch during the whole drying process
- Enables optimization of the freeze drying process cycle
- No influence on the product by short measuring times
- Process data easy to scale-up
- Delivers comprehensive data for better process understanding
For more information please refer to the contact box to the right.